Description
Fresh Picked White Pine Needles.
8oz
Pinus strobus
Eastern White Pine, from the family-owned property in the Southeastern United States. wild grown and harvested in the deep south. Pinus strobus is harvested fresh within 24 hours of shipping. These are very old heirloom trees located in the isolated forest part of the property.
These trees have been a source of much medicine in my family’s chest of treasure to treat many ailments from a common cold, bronchitis, wounds care and treat infections.
Many studies show that pine may assist with diabetes, common infections, pulmonary (lung) infections, and arthritis. White Pine (Pinus strobus) essential oil is one of the most useful and safest therapeutically. Native American Medicine sources say it was used to prevent scurvy and was used in raw form to stuff bedding or mattresses to repel lice and fleas.
Some research shows that it is beneficial for cuts, excessive perspiration, scabies, sores, arthritis, gout, muscular aches and pains, poor circulation, rheumatism, asthma, bronchitis, catarrh, coughs, sinusitis, sore throat, cystitis, urinary infection, colds, flu, fatigue, nervous exhaustion, and stress-related conditions. It is used to stimulate and balance the adrenal glands. Some studies show the needles were used as a tea to show lung congestion and detox system from chemotherapy.
One Korean study demonstrated using pine needles in tea was the best way to access the antioxidant benefits from pine needles. The study demonstrated that the hot water extract of pine needle proanthocyanidins and catechins offer the highest levels of antioxidant benefits compared with chemical extract processes.
There are other known benefits that pine needle tea and the tea made from other conifers share, which include: Analgesic, Antibacterial, Antifungal, Anti-inflammatory, Antimicrobial, Antioxidant, Antiseptic, Antitumor, Antitussive, AntiviralAromatic, Astringent, Decongestant, Detoxifying, Disinfectant, Diuretic, Expectorant, Immuno-modulating, Improves circulation, Invigorating, Lymphatic, Relaxing, Relieves nervous exhaustion and fatigue, Relieves sore muscles, Restorative, Tonic.
Because Suramin is a derivative of the oils in pine needles. The whole herbal source (needles) is superior to the single compound extract (Suramin) – because the needles possess a full complement of phytonutrients providing numerous additional benefits that the extract is incapable of. Now, here is the direct connection between Suramin and Pine Needle Tea.
Needles are 3′-5′ inches long 3-5 needles per section. Tree live
Interesting facts:
Suramin is Derived from Trypan Blue https://en.wikipedia.org/wiki/Trypan_blue
Trypan blue is derived from toluidine, that is, any of several isomeric bases, C14H16N2, derived from toluene. Trypan blue is so-called because it can kill trypanosomes, the parasites that cause sleeping sickness. An analog of trypan blue, suramin, is used pharmacologically against trypanosomiasis. Trypan blue is also known as diamine blue and Niagara blue.
The NATURAL compound was first isolated in 1837 through a distillation of pine oil by the Polish chemist Filip Walter, who named it rétinnaphte. Trypan Blue is a derivative of toluene which is a derivative of pine oil. https://en.wikipedia.org/wiki/Toluene
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REFERENCES:
Filip Neriusz Walter – Wikipedia
Eastern White Pine Tree Needles a Natural Source of Suramin (biologicalmedicineinstitute.com)
Eastern White Pine DatabasePinus strobus L (usda.gov)
American Journal of Medicine, The – Search Results (amjmed.com)
Xu, H. Eric, Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao et al. “Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19.” (2020).
Yin, W. et al. (2020). Structural Basis For Repurposing A 100-Years-Old Drug Suramin For Treating COVID-19. bioRxiv preprint. doi: https://doi.org/10.1101/2020.10.06.328336. https://www.biorxiv.org/content/10.1101/2020.10.06.328336v1
Salgado-Benvindo, C. et al. Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle. Antimicrob Agents Chemother 64(2020)
Albulescu, I.C., Kovacikova, K., Tas, A., Snijder, E.J., and van Hemert, M.J. (2017). Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. Antiviral Res 143, 230-236.
Henß, L. et al. Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry. Virol J 13, 149 (2016).
Ren, P., Zou, G., Bailly, B., Xu, S., Zeng, M., Chen, X., Shen, L., Zhang, Y., Guillon, P., Arenzana-Seisdedos, F., et al. (2014). The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo. Emerging microbes & infections 3, e62.
Albulescu, I.C., van Hoolwerff, M., Wolters, L.A., Bottaro, E., Nastruzzi, C., Yang, S.C., Tsay, S.-C., Hwu, J.R., Snijder, E.J., and van Hemert, M.J. (2015). Suramin inhibits chikungunya virus replication through multiple mechanisms. Antiviral Research 121, 39-46.
Zoltner, Martin, Gustavo D. Campagnaro, Gergana Taleva, Alana Burrell, Michela Cerone, Ka-Fai Leung, Fiona Achcar et al. “Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes.” Journal of Biological Chemistry 295, no. 24 (2020): 8331-8347.
De Clercq, Erik. “Suramin in the treatment of AIDS: mechanism of action.” Antiviral research 7, no. 1 (1987): 1-10.
Kartnig, Theodor, Franz Still, and Franz Reinthaler. “Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.).” Journal of ethnopharmacology 35, no. 2 (1991): 155-157.
Croci, R., Pezzullo, M., Tarantino, D., Milani, M., Tsay, S.-C., Sureshbabu, R., Tsai, Y.-J., Mastrangelo, E., Rohayem, J., Bolognesi, M., et al. (2014). Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds. PloS one 9, e91765-e91765.
Cheng, B., Gao, F., Maissy, E., and Xu, P. (2019). Repurposing suramin for the treatment of breast cancer lung metastasis with glycol chitosan-based nanoparticles. Acta Biomater 84, 378-390.
Myers, Charles, Michael Cooper, Cy Stein, Renato LaRocca, M. M. Walther, Gary Weiss, Peter Choyke, Nancy Dawson, Seth Steinberg, and Margaret M. Uhrich. “Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer.” Journal of clinical oncology 10, no. 6 (1992): 881-889.
Stein, C. A., R. V. LaRocca, R. Thomas, N. McAtee, and Charles E. Myers. “Suramin: an anticancer drug with a unique mechanism of action.” Journal of Clinical Oncology 7, no. 4 (1989): 499-508.
Mooon, Jeong-jo, Young-bok Han, and Jin-suk Kim. “Studies on antitumor effects of pine needles, Pinus densiflora Sieb. et Zucc.” Korean Journal of Veterinary Research 33, no. 4 (1993): 701-710.
Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O’Brien, Ronald Barr, and Ronald McCaffrey. “Antiproliferative effects of suramin on lymphoid cells.” Cancer research 47, no. 17 (1987): 4694-4698.
Kathir, Karuppanan Muthusamy, Thallapuranam Krishnaswamy S. Kumar, and Chin Yu. “Understanding the mechanism of the antimitogenic activity of suramin.” Biochemistry 45, no. 3 (2006): 899-906
https://pubchem.ncbi.nlm.nih.gov/compound/Suramin-sodium
Hosang, Markus. “Suramin binds to platelet‐derived growth factor and inhibits its biological activity.” Journal of cellular biochemistry 29, no. 3 (1985): 265-273.
Betsholtz, Christer, Ann Johnsson, Carl-Henrik Heldin, and Bengt Westermark. “Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.” Proceedings of the National Academy of Sciences 83, no. 17 (1986): 6440-6444.
Coffey Jr, Robert J., Edward B. Leof, Gary D. Shipley, and Harold L. Moses. “Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells.” Journal of cellular physiology 132, no. 1 (1987): 143-148.
Sartor, Oliver, Catherine A. McLellan, Charles E. Myers, and M. M. Borner. “Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines.” The Journal of clinical investigation 90, no. 6 (1992): 2166-2174
